Postdoctoral Researcher in parasitology/structural biology
Postdoctoral Researcher
in parasitology/structural biology
The HiLIFE - Institute of Biotechnology at the University of Helsinki, renowned for its international research excellence, is excited to announce an opening for a postdoctoral researcher to join the newly formed group of Dr. Alexander Mühleip.
Project Description
The research of the group is focused on understanding how protein complexes organise mitochondrial membranes in protozoan parasites and when disrupted by human mitochondrial disorders. The successful applicant will work on the structural and functional characterisation of protein complexes involved in mitochondrial energy conversion in malaria parasites using protein biochemistry, single-particle cryo-EM and in-situ cryo-electron tomography. Specifically, the project is aimed at visualisation of inner-membrane architecture and characterising parasite-specific modulation of membrane biogenesis. The project offers the unique opportunity to combine parasitology and mitochondrial biology with state-of-the-art structural biology techniques. The group benefits from in-house availability of a 200-kV Talos Artica microscope, complemented by access to 300-kV cryo-electron microscopes for data collection at international facilities.
About you
• you are ambitious, goal-oriented, collegial and motivated to tackle challenging new projects
• PhD degree (or be in the final stages of PhD submission) in cell/molecular biology, parasitology, protein biochemistry or a similar field
• prior experience in cultivation of Plasmodium falciparum is essential
• expertise in genetic engineering (e.g. CRISPR/Cas9) is strongly desired
• high interest in learning structural biology methods (comprehensive cryo-EM training will be provided)
• commitment to scientific excellence as demonstrated by a strong publication record
• excellent command of English (working language at the institute)
• strong communication, interpersonal, organizational and time management skills
What we offer
• a fixed-term 3-year position with possible extension
• a collaborative, innovative and inclusive work environment
• support and mentoring for postdoctoral fellowship applications (EMBO, Marie-Curie etc.)
• a competitive salary depending on your qualifications and personal performance, 5-7 weeks of annual holiday leave, flexible working hours
• financial support with Finnish visa and residency permits, if applicable
• occupational health care and access to high-quality sports facilities
About the Institute of Biotechnology, HiLIFE, University of Helsinki
The Institute of Biotechnology is an independent research institute within the Helsinki Institute of Life Science (HiLIFE), at the University of Helsinki, Finland, and at the global forefront of life science research with state-of-the-art research core facilities in genomics, biological imaging and structural biology. According to the 2024 Times Higher Education World University survey, the University of Helsinki is ranked among the top 80 universities world-wide in life science research. The University of Helsinki is committed to providing a welcoming environment for international researchers, offering comprehensive services and support for relocating to Finland—a country known for its high quality of life, excellent education system, and robust support for research and innovation.
How to apply?
Welcome with your application in English (click the ‘apply’ link), as soon as possible or no later than April 28th. Please note that applications will be continually reviewed. The position is available immediately or according to mutual agreement. Applications should include a cover letter, CV, and contact details of three references. For further information on the position, please contact Alexander Mühleip (alexander.muhleip@helsinki.fi).