Postdoctoral Researcher, Alternative Splicing Regulation in Human Diseases
Postdoctoral Researcher, Alternative Splicing Regulation in Human Diseases
The Chen’s research group (https://www.chen-sysimeta-lab.com) at the Faculty of Medicine, University of Helsinki invites applications for a Postdoctoral Researcher position. The position is available immediately with flexibility on the starting date. The position is initially for 1 year, with the possibility for extension through application for further funding by the applicant and PI.
Our research
We conduct data-driven research to understand the pathogenesis of human diseases, with a focus on metabolic disorders, such as obesity, metabolic dysfunction-associated steatotic liver disease, type 2 diabetes, and cancers. In close collaboration with multidisciplinary researchers, we integrate biobank resources, clinical data, omics technologies, as well as novel computational approaches to uncover the cellular and molecular mechanisms driving disease development and progression. A key objective of our work is to develop advanced computational tools to dissect the role of alternative splicing in these diseases.
The postdoctoral fellows will work on computational method development and data analysis for bulk and single-cell omics data from human patient samples. Individuals with a strong interest and background in computational biology/bioinformatics are strongly encouraged to consider this opportunity. Our research is funded by the Research Council of Finland, Sigrid Jusélius Foundation, the Digital Precision Cancer Medicine Flagship (iCAN), and among others.
Your mission
To qualify, applicants must hold a PhD in computational biology and possess extensive knowledge of biomedical sciences. A strong publication record and a solid background in computational RNA biology, particularly in alternative splicing regulation, are our top priorities. Expertise in machine learning and human omics data analysis is highly advantageous. The ideal candidate should demonstrate a high level of independence while also valuing collaboration and teamwork. Strong motivation, the ability to work across disciplines, excellent organizational skills, and effective communication in English are essential. Experience with biopsy specimen collection, flow cytometry, cell culture, and library construction for single-cell sequencing is beneficial but not required. Additionally, candidates will have the opportunity to co-mentor doctoral and master’s students.
What we offer
The selected candidate will benefit from University of Helsinki staff advantages, including occupational health care and health insurance, unemployment and pension fund, a generous holiday package, sports facilities, and opportunities for professional development: https://www.helsinki.fi/en/about-us/careers. Additionally, they will have access to high-quality public childcare, schools, and generous family benefits. The position requires the candidate to be based in Finland while employed by the University of Helsinki. Our HR services provide comprehensive support to international employees, ensuring a smooth transition to living and working in Finland.
Our lab fosters a collaborative and dynamic research environment, leveraging an extensive international scientific network. This position offers a unique opportunity to expand your research connections while working with cutting-edge omics technologies and computational methods to drive impactful discoveries in obesity and cancer research.
The salary will be based on the University salary scheme for research and teaching staff. The starting salary will be ca. 3 700 euros/month. Employment is expected to start in March 2025, or agreed, at fixed 1-year position, with a possibility of prolongation. A 6-month trial period will be applied.
How to apply
Applications should be submitted through the University of Helsinki Recruitment System via the "Apply now" button.
Internal applicants (i.e., current employees of the University of Helsinki) submit their applications by using the Employee Login button.
Please send your application with following enclosures:
- A complete CV, including PhD thesis title and date of defense, previous and current positions, academic distinctions, teaching and committee work
- A complete list of publications
- A summary of current research work (half page) and research vision for postdoctoral goals (half page)
The closing date for applications is March 5th, 2025.
For further information on the position, please contact Dr. Ping Chen: ping.chen (at) helsinki.fi.
The University of Helsinki welcomes applicants of any gender and age, linguistic or cultural background, or minority group.
About us
The Faculty of Medicine promotes high-quality scientific research and provides research-based undergraduate and postgraduate education in medicine, dentistry, psychology, and logopedics, as well as an international Master's Programme in Translational Medicine. In addition to its teaching and research activities, the faculty serves as a significant expert organization in the healthcare sector and contributes to ethical discourse in the field.
Together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE), the Faculty of Medicine constitutes an academic medical centre recognized for excellence in international comparisons.
JOIN US TO BUILD A BETTER WORLD – TOGETHER!
#HelsinkiUniCareers